BET inhibition disrupts transcription but retains enhancer-promoter contact

Enhancers are DNA sequences that enable complex temporal and tissue-specific regulation of genes in higher eukaryotes. Although it is not entirely clear how enhancer-promoter interactions can increase gene expression, this proximity has been observed in multiple systems at multiple loci and is thoug...

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Detalles Bibliográficos
Autores principales: Crump, Nicholas T., Ballabio, Erica, Godfrey, Laura, Thorne, Ross, Repapi, Emmanouela, Kerry, Jon, Tapia, Marta, Hua, Peng, Lagerholm, Christoffer, Filippakopoulos, Panagis, Davies, James O. J., Milne, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801379/
https://www.ncbi.nlm.nih.gov/pubmed/33431820
http://dx.doi.org/10.1038/s41467-020-20400-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801379/
https://www.ncbi.nlm.nih.gov/pubmed/33431820
http://dx.doi.org/10.1038/s41467-020-20400-z

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