Development of phenotypic assays for identifying novel blockers of L-type calcium channels in neurons

L-type calcium channels (LTCCs) are highly expressed in the heart and brain and are critical for cardiac and neuronal functions. LTCC-blocking drugs have a long and successful record in the clinic for treating cardiovascular disorders. In contrast, establishment of their efficacy for indications of...

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Detalles Bibliográficos
Autores principales: Hagan, Rebecca, Rex, Elizabeth, Woody, David, Milewski, Monika, Glaza, Thomas, Maher, Michael P., Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801380/
https://www.ncbi.nlm.nih.gov/pubmed/33432098
http://dx.doi.org/10.1038/s41598-020-80692-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801380/
https://www.ncbi.nlm.nih.gov/pubmed/33432098
http://dx.doi.org/10.1038/s41598-020-80692-5

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