CHIP promotes Wnt signaling and regulates Arc stability by recruiting and polyubiquitinating LEF1 or Arc

The carboxyl terminus of Hsc70-interacting protein (CHIP), an E3 ubiquitin ligase, participates in many cellular processes such as protein degradation, trafficking, autophagy, apoptosis, and multiple signaling transductions. The mutant of CHIP (p.T246M) causes the spinocerebellar autosomal recessive...

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Detalles Bibliográficos
Autores principales: Liu, Yuchun, Sun, Yao, Huang, Yonghui, Cheng, Kang, Xu, Yuming, Tian, Qingnan, Zhang, Shoutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801388/
https://www.ncbi.nlm.nih.gov/pubmed/33431799
http://dx.doi.org/10.1038/s41420-020-00394-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801388/
https://www.ncbi.nlm.nih.gov/pubmed/33431799
http://dx.doi.org/10.1038/s41420-020-00394-9

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