Mitochondrial gene expression in single cells shape pancreatic beta cells' sub-populations and explain variation in insulin pathway

Mitochondrial gene expression is pivotal to cell metabolism. Nevertheless, it is unknown whether it diverges within a given cell type. Here, we analysed single-cell RNA-seq experiments from human pancreatic alpha (N = 3471) and beta cells (N = 1989), as well as mouse beta cells (N = 1094). Cluster a...

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Detalles Bibliográficos
Autores principales: Medini, H., Cohen, T., Mishmar, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801437/
https://www.ncbi.nlm.nih.gov/pubmed/33432158
http://dx.doi.org/10.1038/s41598-020-80334-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801437/
https://www.ncbi.nlm.nih.gov/pubmed/33432158
http://dx.doi.org/10.1038/s41598-020-80334-w

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