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CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis

Epigenetic alterations play an important role in tumor progression of diffuse large B-cell lymphoma (DLBCL). However, the biological relevance of epigenetic gene mutations on tumor microenvironment remains to be determined. The core set of genes relating to histone methylation (KMT2D, KMT2C, EZH2),...

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Detalles Bibliográficos
Autores principales: Huang, Yao-Hui, Cai, Kun, Xu, Peng-Peng, Wang, Li, Huang, Chuan-Xin, Fang, Ying, Cheng, Shu, Sun, Xiao-Jian, Liu, Feng, Huang, Jin-Yan, Ji, Meng-Meng, Zhao, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801454/
https://www.ncbi.nlm.nih.gov/pubmed/33431788
http://dx.doi.org/10.1038/s41392-020-00437-8