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Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism

Regeneration failure after spinal cord injury (SCI) results in part from the lack of a pro-regenerative response in injured neurons, but the response to SCI has not been examined specifically in injured sensory neurons. Using RNA sequencing of dorsal root ganglion, we determined that thoracic SCI el...

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Detalles Bibliográficos
Autores principales: Ewan, Eric E., Avraham, Oshri, Carlin, Dan, Gonçalves, Tassia Mangetti, Zhao, Guoyan, Cavalli, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801468/
https://www.ncbi.nlm.nih.gov/pubmed/33431991
http://dx.doi.org/10.1038/s41598-020-79624-0