Cargando…

Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome

Cytosolic inflammasomes are supramolecular complexes that are formed in response to intracellular pathogens and danger signals. However, as to date, the detailed description of a homotypic caspase recruitment domain (CARD) interaction between NLRP1 and ASC has not been presented. We found the CARD–C...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Zhihao, Zhou, Ying, Liu, Muziying, Ma, Huan, Sun, Liangqi, Zahid, Ayesha, Chen, Yulei, Zhou, Rongbin, Cao, Minjie, Wu, Dabao, Zhao, Weidong, Li, Bofeng, Jin, Tengchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801473/
https://www.ncbi.nlm.nih.gov/pubmed/33431827
http://dx.doi.org/10.1038/s41419-020-03342-8