Cargando…
Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome
Cytosolic inflammasomes are supramolecular complexes that are formed in response to intracellular pathogens and danger signals. However, as to date, the detailed description of a homotypic caspase recruitment domain (CARD) interaction between NLRP1 and ASC has not been presented. We found the CARD–C...
| Autores principales: | , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801473/ https://www.ncbi.nlm.nih.gov/pubmed/33431827 http://dx.doi.org/10.1038/s41419-020-03342-8 |