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LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding

Most mitochondrial precursor polypeptides are imported from the cytosol into the mitochondrion, where they must efficiently undergo folding. Mitochondrial precursors are imported as unfolded polypeptides. For proteins of the mitochondrial matrix and inner membrane, two separate chaperone systems, HS...

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Detalles Bibliográficos
Autores principales: Shin, Chun-Shik, Meng, Shuxia, Garbis, Spiros D., Moradian, Annie, Taylor, Robert W., Sweredoski, Michael J., Lomenick, Brett, Chan, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801493/
https://www.ncbi.nlm.nih.gov/pubmed/33431889
http://dx.doi.org/10.1038/s41467-020-20597-z