ABCA8-mediated efflux of taurocholic acid contributes to gemcitabine insensitivity in human pancreatic cancer via the S1PR2-ERK pathway

The development of resistance to anticancer drugs is believed to cause chemotherapy failure in pancreatic cancer (PC). The efflux of anticancer drugs mediated by ATP-binding cassette (ABC) transporters is a widely accepted mechanism for chemoresistance, but for ABCA subfamily members, which are char...

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Detalles Bibliográficos
Autores principales: Yang, Chunmei, Yuan, Hui, Gu, Jinyang, Xu, Dengfei, Wang, Mingwei, Qiao, Jie, Yang, Xi, Zhang, Jian, Yao, Ming, Gu, Jianren, Tu, Hong, Gan, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801517/
https://www.ncbi.nlm.nih.gov/pubmed/33431858
http://dx.doi.org/10.1038/s41420-020-00390-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801517/
https://www.ncbi.nlm.nih.gov/pubmed/33431858
http://dx.doi.org/10.1038/s41420-020-00390-z

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