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ABCA8-mediated efflux of taurocholic acid contributes to gemcitabine insensitivity in human pancreatic cancer via the S1PR2-ERK pathway

The development of resistance to anticancer drugs is believed to cause chemotherapy failure in pancreatic cancer (PC). The efflux of anticancer drugs mediated by ATP-binding cassette (ABC) transporters is a widely accepted mechanism for chemoresistance, but for ABCA subfamily members, which are char...

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Detalles Bibliográficos
Autores principales:	Yang, Chunmei, Yuan, Hui, Gu, Jinyang, Xu, Dengfei, Wang, Mingwei, Qiao, Jie, Yang, Xi, Zhang, Jian, Yao, Ming, Gu, Jianren, Tu, Hong, Gan, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801517/ https://www.ncbi.nlm.nih.gov/pubmed/33431858 http://dx.doi.org/10.1038/s41420-020-00390-z

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