PBK phosphorylates MSL1 to elicit epigenetic modulation of CD276 in nasopharyngeal carcinoma

CD276 (also known as B7–H3, an immune checkpoint molecule) is aberrantly overexpressed in many cancers. However, the upregulation mechanism and in particular, whether oncogenic signaling has a role, is unclear. Here we demonstrate that a pro-oncogenic kinase PBK, the expression of which is associate...

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Detalles Bibliográficos
Autores principales: Wang, Meng-Yao, Qi, Bin, Wang, Fang, Lin, Zhi-Rui, Li, Ming-Yi, Yin, Wen-Jing, Zhu, Yan-Yi, He, Lu, Yu, Yi, Yang, Fang, Liu, Jin-Quan, Chen, Dong-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801519/
https://www.ncbi.nlm.nih.gov/pubmed/33431797
http://dx.doi.org/10.1038/s41389-020-00293-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801519/
https://www.ncbi.nlm.nih.gov/pubmed/33431797
http://dx.doi.org/10.1038/s41389-020-00293-9

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