Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution

Infection of the human stomach by Helicobacter pylori remains a worldwide problem and greatly contributes to peptic ulcer disease and gastric cancer. Without active intervention approximately 50% of the world population will continue to be infected with this gastric pathogen. Current eradication, ca...

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Detalles Bibliográficos
Autores principales: Cunha, Eva S., Chen, Xiaorui, Sanz-Gaitero, Marta, Mills, Deryck J., Luecke, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801526/
https://www.ncbi.nlm.nih.gov/pubmed/33431861
http://dx.doi.org/10.1038/s41467-020-20485-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801526/
https://www.ncbi.nlm.nih.gov/pubmed/33431861
http://dx.doi.org/10.1038/s41467-020-20485-6

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