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Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution
Infection of the human stomach by Helicobacter pylori remains a worldwide problem and greatly contributes to peptic ulcer disease and gastric cancer. Without active intervention approximately 50% of the world population will continue to be infected with this gastric pathogen. Current eradication, ca...
Autores principales: | Cunha, Eva S., Chen, Xiaorui, Sanz-Gaitero, Marta, Mills, Deryck J., Luecke, Hartmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801526/ https://www.ncbi.nlm.nih.gov/pubmed/33431861 http://dx.doi.org/10.1038/s41467-020-20485-6 |
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