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Impact of 12-month cryopreservation on endogenous DNA damage in whole blood and isolated mononuclear cells evaluated by the comet assay

The comet assay is an electrophoretic technique used to assess DNA damage, as a marker of genotoxicity and oxidative stress, in tissues and biological samples including peripheral blood mononuclear cells (PBMCs) and whole blood (WB). Although numerous studies are performed on stored samples, the imp...

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Detalles Bibliográficos
Autores principales: Marino, Mirko, Gigliotti, Letizia, Møller, Peter, Riso, Patrizia, Porrini, Marisa, Del Bo, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801598/
https://www.ncbi.nlm.nih.gov/pubmed/33432000
http://dx.doi.org/10.1038/s41598-020-79670-8