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Impact of 12-month cryopreservation on endogenous DNA damage in whole blood and isolated mononuclear cells evaluated by the comet assay
The comet assay is an electrophoretic technique used to assess DNA damage, as a marker of genotoxicity and oxidative stress, in tissues and biological samples including peripheral blood mononuclear cells (PBMCs) and whole blood (WB). Although numerous studies are performed on stored samples, the imp...
Autores principales: | Marino, Mirko, Gigliotti, Letizia, Møller, Peter, Riso, Patrizia, Porrini, Marisa, Del Bo, Cristian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801598/ https://www.ncbi.nlm.nih.gov/pubmed/33432000 http://dx.doi.org/10.1038/s41598-020-79670-8 |
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