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SP1-induced long non-coding RNA SNHG6 facilitates the carcinogenesis of chondrosarcoma through inhibiting KLF6 by recruiting EZH2

Small nucleolar RNA host gene 6 (SNHG6) is a newly discovered long non-coding RNA (lncRNA), while the regulatory mechanism of SNHG6 in chondrosarcoma is largely unknown. Here we found that SNHG6 expression was upregulated and showed positive correlation with the progression of chondrosarcoma. Functi...

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Detalles Bibliográficos
Autores principales: Pu, Fei-Fei, Shi, De-Yao, Chen, Ting, Liu, Yu-Xuan, Zhong, Bin-Long, Zhang, Zhi-Cai, Liu, Wei-Jian, Wu, Qiang, Wang, Bai-Chuan, Shao, Zeng-Wu, He, Tong-Chuan, Liu, Jian-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801621/
https://www.ncbi.nlm.nih.gov/pubmed/33431838
http://dx.doi.org/10.1038/s41419-020-03352-6