The Aβ(1–38) peptide is a negative regulator of the Aβ(1–42) peptide implicated in Alzheimer disease progression

The pool of β-Amyloid (Aβ) length variants detected in preclinical and clinical Alzheimer disease (AD) samples suggests a diversity of roles for Aβ peptides. We examined how a naturally occurring variant, e.g. Aβ(1–38), interacts with the AD-related variant, Aβ(1–42), and the predominant physiologic...

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Detalles Bibliográficos
Autores principales: Quartey, Maa O., Nyarko, Jennifer N. K., Maley, Jason M., Barnes, Jocelyn R., Bolanos, Maria A. C., Heistad, Ryan M., Knudsen, Kaeli J., Pennington, Paul R., Buttigieg, Josef, De Carvalho, Carlos E., Leary, Scot C., Parsons, Matthew P., Mousseau, Darrell D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801637/
https://www.ncbi.nlm.nih.gov/pubmed/33432101
http://dx.doi.org/10.1038/s41598-020-80164-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801637/
https://www.ncbi.nlm.nih.gov/pubmed/33432101
http://dx.doi.org/10.1038/s41598-020-80164-w

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