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The Aβ(1–38) peptide is a negative regulator of the Aβ(1–42) peptide implicated in Alzheimer disease progression
The pool of β-Amyloid (Aβ) length variants detected in preclinical and clinical Alzheimer disease (AD) samples suggests a diversity of roles for Aβ peptides. We examined how a naturally occurring variant, e.g. Aβ(1–38), interacts with the AD-related variant, Aβ(1–42), and the predominant physiologic...
Autores principales: | Quartey, Maa O., Nyarko, Jennifer N. K., Maley, Jason M., Barnes, Jocelyn R., Bolanos, Maria A. C., Heistad, Ryan M., Knudsen, Kaeli J., Pennington, Paul R., Buttigieg, Josef, De Carvalho, Carlos E., Leary, Scot C., Parsons, Matthew P., Mousseau, Darrell D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801637/ https://www.ncbi.nlm.nih.gov/pubmed/33432101 http://dx.doi.org/10.1038/s41598-020-80164-w |
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