ALKBH5 suppresses tumor progression via an m(6)A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma

ALKBH5 is the main enzyme for m(6)A-based demethylation of RNAs and it has been implicated in many biological and pathophysiological processes. Here, we aimed to explore the potential involvement of ALKBH5 in osteosarcoma and decipher the underlying cellular/molecular mechanisms. We discovered downr...

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Detalles Bibliográficos
Autores principales: Yuan, Ye, Yan, Gege, He, Mingyu, Lei, Hong, Li, Linqiang, Wang, Yang, He, Xiaoqi, Li, Guanghui, Wang, Quan, Gao, Yuelin, Qu, Zhezhe, Mei, Zhongting, Shen, Zhihua, Pu, Jiaying, Wang, Ao, Zhao, Wei, Jiang, Huiwei, Du, Weijie, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801648/
https://www.ncbi.nlm.nih.gov/pubmed/33431791
http://dx.doi.org/10.1038/s41419-020-03315-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801648/
https://www.ncbi.nlm.nih.gov/pubmed/33431791
http://dx.doi.org/10.1038/s41419-020-03315-x

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