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Exposure of Salmonella biofilms to antibiotic concentrations rapidly selects resistance with collateral tradeoffs

Most bacteria in nature exist in biofilms, which are inherently tolerant to antibiotics. There is currently very limited understanding of how biofilms evolve in response to sub-lethal concentrations of antimicrobials. In this study, we use a biofilm evolution model to study the effects of sub-inhibi...

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Detalles Bibliográficos
Autores principales: Trampari, Eleftheria, Holden, Emma R., Wickham, Gregory J., Ravi, Anuradha, Martins, Leonardo de Oliveira, Savva, George M., Webber, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801651/
https://www.ncbi.nlm.nih.gov/pubmed/33431848
http://dx.doi.org/10.1038/s41522-020-00178-0