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Cooperative function of synaptophysin and synapsin in the generation of synaptic vesicle-like clusters in non-neuronal cells

Clusters of tightly packed synaptic vesicles (SVs) are a defining feature of nerve terminals. While SVs are mobile within the clusters, the clusters have no boundaries consistent with a liquid phase. We previously found that purified synapsin, a peripheral SV protein, can assemble into liquid conden...

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Detalles Bibliográficos
Autores principales: Park, Daehun, Wu, Yumei, Lee, Sang-Eun, Kim, Goeun, Jeong, Seonyoung, Milovanovic, Dragomir, De Camilli, Pietro, Chang, Sunghoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801664/
https://www.ncbi.nlm.nih.gov/pubmed/33431828
http://dx.doi.org/10.1038/s41467-020-20462-z