Reference standards for accurate validation and optimization of assays that determine integrated lentiviral vector copy number in transduced cells

Lentiviral vectors (LV) have emerged as a robust technology for therapeutic gene delivery into human cells as advanced medicinal products. As these products are increasingly commercialized, there are concomitant demands for their characterization to ensure safety, efficacy and consistency. Standards...

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Detalles Bibliográficos
Autores principales: Paugh, Barbara S., Baranyi, Lajos, Roy, Andre, He, Hua-Jun, Harris, Lindsay, Cole, Kenneth D., Artlip, Moria, Raimund, Caroline, Langan, Patricia S., Jana, Srikanta, Orentas, Rimas J., Lin-Gibson, Sheng, Krueger, Winfried, Dropulić, Boro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801692/
https://www.ncbi.nlm.nih.gov/pubmed/33431989
http://dx.doi.org/10.1038/s41598-020-79698-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801692/
https://www.ncbi.nlm.nih.gov/pubmed/33431989
http://dx.doi.org/10.1038/s41598-020-79698-w

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