NOD2 deficiency increases retrograde transport of secretory IgA complexes in Crohn’s disease

Intestinal microfold cells are the primary pathway for translocation of secretory IgA (SIgA)-pathogen complexes to gut-associated lymphoid tissue. Uptake of SIgA/commensals complexes is important for priming adaptive immunity in the mucosa. This study aims to explore the effect of SIgA retrograde tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Rochereau, Nicolas, Roblin, Xavier, Michaud, Eva, Gayet, Rémi, Chanut, Blandine, Jospin, Fabienne, Corthésy, Blaise, Paul, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801705/
https://www.ncbi.nlm.nih.gov/pubmed/33431850
http://dx.doi.org/10.1038/s41467-020-20348-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801705/
https://www.ncbi.nlm.nih.gov/pubmed/33431850
http://dx.doi.org/10.1038/s41467-020-20348-0

Ejemplares similares