Lipoxygenase catalyzed metabolites derived from docosahexaenoic acid are promising antitumor agents against breast cancer

Docosahexaenoic acid (DHA) is known to inhibit breast cancer in the rat. Here we investigated whether DHA itself or select metabolites can account for its antitumor action. We focused on metabolites derived from the lipoxygenase (LOX) pathway since we previously showed that they were superior anti-p...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Kun-Ming, Thompson, Henry, Vanden-Heuvel, John P., Sun, Yuan-Wan, Trushin, Neil, Aliaga, Cesar, Gowda, Krishne, Amin, Shantu, Stanley, Bruce, Manni, Andrea, El-Bayoumy, Karam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801725/
https://www.ncbi.nlm.nih.gov/pubmed/33431978
http://dx.doi.org/10.1038/s41598-020-79716-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801725/
https://www.ncbi.nlm.nih.gov/pubmed/33431978
http://dx.doi.org/10.1038/s41598-020-79716-x

Ejemplares similares