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Lipoxygenase catalyzed metabolites derived from docosahexaenoic acid are promising antitumor agents against breast cancer
Docosahexaenoic acid (DHA) is known to inhibit breast cancer in the rat. Here we investigated whether DHA itself or select metabolites can account for its antitumor action. We focused on metabolites derived from the lipoxygenase (LOX) pathway since we previously showed that they were superior anti-p...
Autores principales: | Chen, Kun-Ming, Thompson, Henry, Vanden-Heuvel, John P., Sun, Yuan-Wan, Trushin, Neil, Aliaga, Cesar, Gowda, Krishne, Amin, Shantu, Stanley, Bruce, Manni, Andrea, El-Bayoumy, Karam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801725/ https://www.ncbi.nlm.nih.gov/pubmed/33431978 http://dx.doi.org/10.1038/s41598-020-79716-x |
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