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Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site

Pyroptosis is a new necrosis pattern of hepatocyte during liver inflammation in acute liver failure (ALF). Histone deacetylase 2 (HDAC2) is associated with several pathological conditions in the liver system. The aim of this study is to investigate whether knockdown or pharmacological inhibition of...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Chen, Qian, Jiao, Fangzhou, Shi, Chunxia, Pei, Maohua, Wang, Luwen, Gong, Zuojiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801742/
https://www.ncbi.nlm.nih.gov/pubmed/33431796
http://dx.doi.org/10.1038/s41419-020-03317-9