Hypoxia Increases β-Cell Death by Activating Pancreatic Stellate Cells within the Islet

BACKGROUND: Hypoxia can occur in pancreatic islets in type 2 diabetes mellitus. Pancreatic stellate cells (PSCs) are activated during hypoxia. Here we aimed to investigate whether PSCs within the islet are also activated in hypoxia, causing β-cell injury. METHODS: Islet and primary PSCs were isolate...

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Detalles Bibliográficos
Autores principales: Kim, Jong Jin, Lee, Esder, Ryu, Gyeong Ryul, Ko, Seung-Hyun, Ahn, Yu-Bae, Song, Ki-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801750/
https://www.ncbi.nlm.nih.gov/pubmed/32431113
http://dx.doi.org/10.4093/dmj.2019.0181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801750/
https://www.ncbi.nlm.nih.gov/pubmed/32431113
http://dx.doi.org/10.4093/dmj.2019.0181

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