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Role of Intestinal Microbiota in Metabolism of Voglibose In Vitro and In Vivo

BACKGROUND: Voglibose, an α-glucosidase inhibitor, inhibits breakdown of complex carbohydrates into simple sugar units in intestine. Studies showed that voglibose metabolism in the liver might be negligible due to its poor intestinal absorption. Numerous microorganisms live in intestine and have sev...

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Detalles Bibliográficos
Autores principales: Nepal, Mahesh Raj, Kang, Mi Jeong, Kim, Geon Ho, Cha, Dong Ho, Kim, Ju-Hyun, Jeong, Tae Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801763/
https://www.ncbi.nlm.nih.gov/pubmed/32431100
http://dx.doi.org/10.4093/dmj.2019.0147