Conserved sequence motifs in human TMTC1, TMTC2, TMTC3, and TMTC4, new O-mannosyltransferases from the GT-C/PMT clan, are rationalized as ligand binding sites

BACKGROUND: The human proteins TMTC1, TMTC2, TMTC3 and TMTC4 have been experimentally shown to be components of a new O-mannosylation pathway. Their own mannosyl-transferase activity has been suspected but their actual enzymatic potential has not been demonstrated yet. So far, sequence analysis of T...

Descripción completa

Detalles Bibliográficos
Autores principales: Eisenhaber, Birgit, Sinha, Swati, Jadalanki, Chaitanya K., Shitov, Vladimir A., Tan, Qiao Wen, Sirota, Fernanda L., Eisenhaber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801869/
https://www.ncbi.nlm.nih.gov/pubmed/33436046
http://dx.doi.org/10.1186/s13062-021-00291-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801869/
https://www.ncbi.nlm.nih.gov/pubmed/33436046
http://dx.doi.org/10.1186/s13062-021-00291-w

Ejemplares similares