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Long-chain saturated fatty acid species are not toxic to human pancreatic β-cells and may offer protection against pro-inflammatory cytokine induced β-cell death

Obesity is a major risk factor for type 2 diabetes (T2D) although the causal links remain unclear. A feature shared by both conditions however is systemic inflammation and raised levels of circulating fatty acids (FFA). It is widely believed that in obese individuals genetically prone to T2D, elevat...

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Detalles Bibliográficos
Autores principales: Thomas, Patricia, Leslie, Kaiyven A., Welters, Hannah J., Morgan, Noel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802137/
https://www.ncbi.nlm.nih.gov/pubmed/33435998
http://dx.doi.org/10.1186/s12986-021-00541-8