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Global histone protein surface accessibility in yeast indicates a uniformly loosely packed genome with canonical nucleosomes
BACKGROUND: The vast majority of methods available to characterize genome-wide chromatin structure exploit differences in DNA accessibility to nucleases or chemical crosslinking. We developed a novel method to gauge genome-wide accessibility of histone protein surfaces within nucleosomes by assessin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802155/ https://www.ncbi.nlm.nih.gov/pubmed/33430969 http://dx.doi.org/10.1186/s13072-020-00381-5 |