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Interleukin-6 promotes primitive endoderm development in bovine blastocysts

BACKGROUND: Interleukin-6 (IL6) was recently identified as an embryotrophic factor in bovine embryos, where it acts primarily to mediate inner cell mass (ICM) size. This work explored whether IL6 affects epiblast (EPI) and primitive endoderm (PE) development, the two embryonic lineages generated fro...

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Detalles Bibliográficos
Autores principales: Wooldridge, Lydia K., Ealy, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802221/
https://www.ncbi.nlm.nih.gov/pubmed/33430761
http://dx.doi.org/10.1186/s12861-020-00235-z