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Integration of sperm ncRNA-directed DNA methylation and DNA methylation-directed histone retention in epigenetic transgenerational inheritance

BACKGROUND: Environmentally induced epigenetic transgenerational inheritance of pathology and phenotypic variation has been demonstrated in all organisms investigated from plants to humans. This non-genetic form of inheritance is mediated through epigenetic alterations in the sperm and/or egg to sub...

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Detalles Bibliográficos
Autores principales: Beck, Daniel, Ben Maamar, Millissia, Skinner, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802319/
https://www.ncbi.nlm.nih.gov/pubmed/33436057
http://dx.doi.org/10.1186/s13072-020-00378-0