Morphological study of embryonic Chd8(+/−) mouse brains using light-sheet microscopy

OBJECTIVE: Autism spectrum disorder (ASD) encompasses a group of neurodevelopmental conditions that remain poorly understood due to their genetic complexity. CHD8 is a risk allele strongly associated with ASD, and heterozygous Chd8 loss-of-function mice have been reported to exhibit macrocephaly in...

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Detalles Bibliográficos
Autores principales: Gómez, Harold F., Hodel, Leonie, Michos, Odyssé, Iber, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802325/
https://www.ncbi.nlm.nih.gov/pubmed/33436073
http://dx.doi.org/10.1186/s13104-020-05436-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802325/
https://www.ncbi.nlm.nih.gov/pubmed/33436073
http://dx.doi.org/10.1186/s13104-020-05436-0

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