Cargando…

The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

BACKGROUND: The survival and proliferation of multiple myeloma (MM) cells in the bone marrow (BM) critically depend on interaction with stromal cells expressing the chemokine CXCL12. CXCL12 regulates the homing to the BM niche by mediating the transendothelial migration and adhesion/retention of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Zemin, Lantermans, Hildo, Kuil, Annemieke, Kraan, Willem, Arenzana-Seisdedos, Fernando, Kersten, Marie José, Spaargaren, Marcel, Pals, Steven T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802348/ https://www.ncbi.nlm.nih.gov/pubmed/33436043 http://dx.doi.org/10.1186/s13045-021-01031-3

Ejemplares similares

Correction to: The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma
por: Ren, Zemin, et al.
Publicado: (2021)

Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma
por: Lantermans, Hildo C., et al.
Publicado: (2020)

SDF-1/CXCL12: A Chemokine in the Life Cycle of HIV
por: Arenzana-Seisdedos, Fernando
Publicado: (2015)

CXCL12 is displayed by rheumatoid endothelial cells through its basic amino-terminal motif on heparan sulfate proteoglycans
por: Santiago, Begoña, et al.
Publicado: (2006)

Synthetic heparan sulfate dodecasaccharides reveal single sulfation site interconverts CXCL8 and CXCL12 chemokine biology
por: Jayson, Gordon C., et al.
Publicado: (2015)

Regulation of Cytokine Signaling by B Cell Antigen Receptor and Cd40-Controlled Expression of Heparan Sulfate Proteoglycans
por: van der Voort, Robbert, et al.
Publicado: (2000)

The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain
por: Minderman, Marthe, et al.
Publicado: (2023)

Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization
por: Dyer, Douglas P., et al.
Publicado: (2017)

Tunable Heparan Sulfate Mimetics for Modulating Chemokine Activity
por: Sheng, Gloria J., et al.
Publicado: (2013)

Differential binding of chemokines CXCL1, CXCL2 and CCL2 to mouse glomerular endothelial cells reveals specificity for distinct heparan sulfate domains
por: van Gemst, J. J., et al.
Publicado: (2018)

Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains
por: Monneau, Yoan R., et al.
Publicado: (2017)

Role of heparan sulfate in mediating CXCL8-induced endothelial cell migration
por: Yan, Zhiping, et al.
Publicado: (2016)

Heparan sulfates and heparan sulfate binding proteins in sepsis
por: Liao, Yi-En, et al.
Publicado: (2023)

MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas
por: Minderman, Marthe, et al.
Publicado: (2023)

Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression
por: Nagarajan, Arvindhan, et al.
Publicado: (2018)

Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12
por: O'Boyle, Graeme, et al.
Publicado: (2009)

The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth Factors
por: De Zutter, Alexandra, et al.
Publicado: (2021)

Discovery of rare sulfated N-unsubstituted glucosamine based heparan sulfate analogs selectively activating chemokines
por: Jain, Prashant, et al.
Publicado: (2021)

Immobilization of Heparan Sulfate on Electrospun Meshes to Support Embryonic Stem Cell Culture and Differentiation
por: Meade, Kate A., et al.
Publicado: (2013)

Combinatorial Roles of Heparan Sulfate Proteoglycans and Heparan Sulfates in Caenorhabditis elegans Neural Development
por: Kinnunen, Tarja K.
Publicado: (2014)

Heparan sulfate gets specific
por: Dove, Alan W.
Publicado: (2001)

Heparan sulfate proteoglycans and cancer
por: Blackhall, F H, et al.
Publicado: (2001)

Heparan Sulfate Proteoglycans in Infection
por: Bartlett, Allison H., et al.
Publicado: (2011)

Heparan Sulfate Proteoglycans in Tauopathy
por: Zhu, Yanan, et al.
Publicado: (2022)

The CXCL12γ Chemokine Displays Unprecedented Structural and Functional Properties that Make It a Paradigm of Chemoattractant Proteins
por: Rueda, Patricia, et al.
Publicado: (2008)

A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation
por: Missaghian, Parisa, et al.
Publicado: (2022)

Shape and Function of Interstitial Chemokine CCL21 Gradients Are Independent of Heparan Sulfates Produced by Lymphatic Endothelium
por: Vaahtomeri, Kari, et al.
Publicado: (2021)

Infection and transmission of SARS‐CoV‐2 depend on heparan sulfate proteoglycans
por: Bermejo‐Jambrina, Marta, et al.
Publicado: (2021)

Divergent Synthesis of Heparan Sulfate Oligosaccharides
por: Dulaney, Steven B., et al.
Publicado: (2015)

Heparan sulfate is essential for thymus growth
por: Hsu, Hsuan-Po, et al.
Publicado: (2021)

Dexamethasone Inhibits Heparan Sulfate Biosynthetic System and Decreases Heparan Sulfate Content in Orthotopic Glioblastoma Tumors in Mice
por: Sokolov, Dmitry K., et al.
Publicado: (2023)

Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis
por: Armani-Tourret, Marie, et al.
Publicado: (2021)

Defective angiogenesis in CXCL12 mutant mice impairs skeletal muscle regeneration
por: Hardy, David, et al.
Publicado: (2019)

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis
por: Lemjabbar-Alaoui, Hassan, et al.
Publicado: (2009)

Subsecond Induction of α4 Integrin Clustering by Immobilized Chemokines Stimulates Leukocyte Tethering and Rolling on Endothelial Vascular Cell Adhesion Molecule 1 under Flow Conditions
por: Grabovsky, Valentin, et al.
Publicado: (2000)

Serum heparan sulfate levels are elevated in endotoxemia
por: Hofmann-Kiefer, KF, et al.
Publicado: (2009)

Heparan Sulfate Biosynthesis: Methods for Investigation of the Heparanosome
por: Multhaupt, Hinke A. B., et al.
Publicado: (2012)

Heparan Sulfate-Dependent Enhancement of Henipavirus Infection
por: Mathieu, Cyrille, et al.
Publicado: (2015)

Heparan Sulfate Proteoglycans in Human Colorectal Cancer
por: Vicente, Carolina Meloni, et al.
Publicado: (2018)

Synaptogenesis Is Modulated by Heparan Sulfate in Caenorhabditis elegans
por: Lázaro-Peña, María I., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gkqah7svtqm3dn5gbn9i7jkv92