Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple‐negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways

BACKGROUND: Clinical management of triple-negative breast cancer (TNBC) patients remain challenging because of the development of chemo-resistance. Identification of biomarkers for risk stratification of chemo-resistance and therapeutic decision-making to overcome such resistance is thus necessary....

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Detalles Bibliográficos
Autores principales: Zhu, Shan, Xu, Yulin, Wang, Lijun, Liao, Shichong, Wang, Yuan, Shi, Manman, Tu, Yi, Zhou, Yurong, Wei, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802356/
https://www.ncbi.nlm.nih.gov/pubmed/33430896
http://dx.doi.org/10.1186/s12935-020-01735-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802356/
https://www.ncbi.nlm.nih.gov/pubmed/33430896
http://dx.doi.org/10.1186/s12935-020-01735-5

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