A septin GTPase scaffold of dynein–dynactin motors triggers retrograde lysosome transport

The metabolic and signaling functions of lysosomes depend on their intracellular positioning and trafficking, but the underlying mechanisms are little understood. Here, we have discovered a novel septin GTPase–based mechanism for retrograde lysosome transport. We found that septin 9 (SEPT9) associat...

Descripción completa

Detalles Bibliográficos
Autores principales: Kesisova, Ilona A., Robinson, Benjamin P., Spiliotis, Elias T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802366/
https://www.ncbi.nlm.nih.gov/pubmed/33416861
http://dx.doi.org/10.1083/jcb.202005219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802366/
https://www.ncbi.nlm.nih.gov/pubmed/33416861
http://dx.doi.org/10.1083/jcb.202005219

Ejemplares similares