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Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD

Several potent neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus have been identified. However, antibody-dependent enhancement (ADE) has not been comprehensively studied for SARS-CoV-2, and the relationship between enhancing versus neutralizing activi...

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Detalles Bibliográficos
Autores principales: Zhou, Yunjiao, Liu, Zezhong, Li, Shibo, Xu, Wei, Zhang, Qianqian, Silva, Israel T., Li, Cheng, Wu, Yanling, Jiang, Qingling, Liu, Zhenmi, Wang, Qiujing, Guo, Yu, Wu, Jianbo, Gu, Chengjian, Cai, Xia, Qu, Di, Mayer, Christian T., Wang, Xiangxi, Jiang, Shibo, Ying, Tianlei, Yuan, Zhenghong, Xie, Youhua, Wen, Yumei, Lu, Lu, Wang, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802522/
https://www.ncbi.nlm.nih.gov/pubmed/33485405
http://dx.doi.org/10.1016/j.celrep.2021.108699