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Knockout of calpain‐1 protects against high‐fat diet‐induced liver dysfunction in mouse through inhibiting oxidative stress and inflammation

The present study was designed to investigate the significance of calpain‐1 in the high‐fat diet (HFD)‐induced liver dysfunction and to explore the possible mechanism. C57 mice and calpain‐1 knockout (KO) mice were fed with standard diet (SD) or HFD, respectively, for 16 weeks. The activities of cal...

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Detalles Bibliográficos
Autores principales: Xu, Hao, Zhang, Li, Xu, Duowen, Deng, Weibo, Yang, Wenbao, Tang, Futian, Da, Mingxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802557/
https://www.ncbi.nlm.nih.gov/pubmed/33473299
http://dx.doi.org/10.1002/fsn3.2002