Topical Nano-Vesicular Spanlastics of Celecoxib: Enhanced Anti-Inflammatory Effect and Down-Regulation of TNF-α, NF-кB and COX-2 in Complete Freund’s Adjuvant-Induced Arthritis Model in Rats

BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease that underlies chronic inflammation of the synovial membrane. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat RA. However, a long list of adverse events associated with long-term treatment regimens with NSAIDs n...

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Detalles Bibliográficos
Autores principales: Alaaeldin, Eman, Abou-Taleb, Heba A, Mohamad, Soad A, Elrehany, Mahmoud, Gaber, Shereen S, Mansour, Heba F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802787/
https://www.ncbi.nlm.nih.gov/pubmed/33447032
http://dx.doi.org/10.2147/IJN.S289828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802787/
https://www.ncbi.nlm.nih.gov/pubmed/33447032
http://dx.doi.org/10.2147/IJN.S289828

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