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PremPS: Predicting the impact of missense mutations on protein stability

Computational methods that predict protein stability changes induced by missense mutations have made a lot of progress over the past decades. Most of the available methods however have very limited accuracy in predicting stabilizing mutations because existing experimental sets are dominated by mutat...

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Detalles Bibliográficos
Autores principales: Chen, Yuting, Lu, Haoyu, Zhang, Ning, Zhu, Zefeng, Wang, Shuqin, Li, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802934/
https://www.ncbi.nlm.nih.gov/pubmed/33378330
http://dx.doi.org/10.1371/journal.pcbi.1008543