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A genetic screen in Drosophila reveals an unexpected role for the KIP1 ubiquitination-promoting complex in male fertility

A unifying feature of polycystin-2 channels is their localization to both primary and motile cilia/flagella. In Drosophila melanogaster, the fly polycystin-2 homologue, Amo, is an ER protein early in sperm development but the protein must ultimately cluster at the flagellar tip in mature sperm to be...

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Detalles Bibliográficos
Autores principales: Li, Weizhe, Liang, Jinqing, Outeda, Patricia, Turner, Stacey, Wakimoto, Barbara T., Watnick, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802972/
https://www.ncbi.nlm.nih.gov/pubmed/33378371
http://dx.doi.org/10.1371/journal.pgen.1009217