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Computational deconvolution to estimate cell type-specific gene expression from bulk data

Computational deconvolution is a time and cost-efficient approach to obtain cell type-specific information from bulk gene expression of heterogeneous tissues like blood. Deconvolution can aim to either estimate cell type proportions or abundances in samples, or estimate how strongly each present cel...

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Detalles Bibliográficos
Autores principales: Jaakkola, Maria K, Elo, Laura L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803005/
https://www.ncbi.nlm.nih.gov/pubmed/33575652
http://dx.doi.org/10.1093/nargab/lqaa110