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Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells

In response to physiological demand, the pituitary gland generates new hormone-secreting cells from committed progenitor cells throughout life. It remains unclear to what extent pituitary stem cells (PSCs), which uniquely express SOX2, contribute to pituitary growth and renewal. Moreover, neither th...

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Detalles Bibliográficos
Autores principales: Russell, John P, Lim, Xinhong, Santambrogio, Alice, Yianni, Val, Kemkem, Yasmine, Wang, Bruce, Fish, Matthew, Haston, Scott, Grabek, Anaëlle, Hallang, Shirleen, Lodge, Emily J, Patist, Amanda L, Schedl, Andreas, Mollard, Patrice, Nusse, Roel, Andoniadou, Cynthia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803373/
https://www.ncbi.nlm.nih.gov/pubmed/33399538
http://dx.doi.org/10.7554/eLife.59142