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Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
In response to physiological demand, the pituitary gland generates new hormone-secreting cells from committed progenitor cells throughout life. It remains unclear to what extent pituitary stem cells (PSCs), which uniquely express SOX2, contribute to pituitary growth and renewal. Moreover, neither th...
Autores principales: | Russell, John P, Lim, Xinhong, Santambrogio, Alice, Yianni, Val, Kemkem, Yasmine, Wang, Bruce, Fish, Matthew, Haston, Scott, Grabek, Anaëlle, Hallang, Shirleen, Lodge, Emily J, Patist, Amanda L, Schedl, Andreas, Mollard, Patrice, Nusse, Roel, Andoniadou, Cynthia L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803373/ https://www.ncbi.nlm.nih.gov/pubmed/33399538 http://dx.doi.org/10.7554/eLife.59142 |
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