Thresholds for post-rebound SHIV control after CCR5 gene-edited autologous hematopoietic cell transplantation

Autologous, CCR5 gene-edited hematopoietic stem and progenitor cell (HSPC) transplantation is a promising strategy for achieving HIV remission. However, only a fraction of HSPCs can be edited ex vivo to provide protection against infection. To project the thresholds of CCR5-edition necessary for HIV...

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Detalles Bibliográficos
Autores principales: Cardozo-Ojeda, E Fabian, Duke, Elizabeth R, Peterson, Christopher W, Reeves, Daniel B, Mayer, Bryan T, Kiem, Hans-Peter, Schiffer, Joshua T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803377/
https://www.ncbi.nlm.nih.gov/pubmed/33432929
http://dx.doi.org/10.7554/eLife.57646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803377/
https://www.ncbi.nlm.nih.gov/pubmed/33432929
http://dx.doi.org/10.7554/eLife.57646

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