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Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17

After optic nerve crush (ONC), the cell bodies and distal axons of most retinal ganglion cells (RGCs) degenerate. RGC somal and distal axon degenerations were previously thought to be controlled by two parallel pathways, involving activation of the kinase dual leucine-zipper kinase (DLK) and loss of...

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Detalles Bibliográficos
Autores principales: Niu, Jingwen, Sanders, Shaun S., Jeong, Hey-Kyeong, Holland, Sabrina M., Sun, Yue, Collura, Kaitlin M., Hernandez, Luiselys M., Huang, Haoliang, Hayden, Michael R., Smith, George M., Hu, Yang, Jin, Yishi, Thomas, Gareth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803378/
https://www.ncbi.nlm.nih.gov/pubmed/33207199
http://dx.doi.org/10.1016/j.celrep.2020.108365