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Multiplexed clonality verification of cell lines for protein biologic production
During the development of cell lines for therapeutic protein production, a vector harboring a product transgene is integrated into the genome. To ensure production stability and consistent product quality, single-cell cloning is then performed. Since cells derived from the same parental clone have t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803388/ https://www.ncbi.nlm.nih.gov/pubmed/32034880 http://dx.doi.org/10.1002/btpr.2978 |