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Multiplexed clonality verification of cell lines for protein biologic production

During the development of cell lines for therapeutic protein production, a vector harboring a product transgene is integrated into the genome. To ensure production stability and consistent product quality, single-cell cloning is then performed. Since cells derived from the same parental clone have t...

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Detalles Bibliográficos
Autores principales: O’Brien, Sofie A., Ojha, Juhi, Wu, Paul, Hu, Wei-Shou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803388/
https://www.ncbi.nlm.nih.gov/pubmed/32034880
http://dx.doi.org/10.1002/btpr.2978

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